Six victories from their last seven league games have seen United move third in the table, a place and a point above the Gunners with a game in hand.
"We want to win the title so we have to get three points there," said Ronaldo.
"We have a great spirit and we are a great team, so our aim is to pick up three points."
Despite their impressive past record on their visits to Highbury, Arsenal`s previous home, United have claimed just one point from two games at the Emirates Stadium.
But Arsenal have gone three games without a win in all competitions and, despite sitting fourth in the table, have already lost to Fulham and Hull this season.
Gunners boss Arsene Wenger is definitely without top-scorer Emmanuel Adebayor, while Mikael Silvestre has a suspected broken nose, Theo Walcott and William Gallas are doubts and Robin van Persie begins a three-match domestic suspension.

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